
Hi,
We had a Leo with AF.
She had it from about 4 years till she died at 10 years old.
We tried everything else than the surgery (could not find a vet that had enough experience in doing the surgery)
Believe or not, Herbal/natural medicines to treat/support her immune system as a whole were the best before we found the immune suppressants (sp?)!
She was very ill indeed, her seasons stopped and she just looked unwell as a whole and at one point like a hippo because the vet was pumping her full of cortisone which made her very bloated.
After starting her on the immune suppressants her bum healed and as a whole she looked so much better and even started her seasons again.
When she was started on the immune medication she was on a human version of Atopica, Sandimmun Neoral for few years.
Which by the way was slightly cheaper than Atopica so might be worth seeing if you can get this instead of Atopica?
She had blood panels every 6 months and those were always fine.
When she was started on the medication she was on a 200mg/twice a day Sandimmun Neoral (the human version) and in the end her "upkeep" dose was Atopica 100mg/day.
We tried weaning her off the Atopica but the holes returned, we also had to top the dose if she was having a season.
We wanted to spay her but first she lost her seasons and was very unwell so we didn't and then she was getting on for a large dog so we never did.
In hind sight I hope we had gone through the spay when she was 7, as seasons did always flare up her bum if we didn't rise the dose up early enough.
Only side effect our girl had was stiffness in her joints(our vet said this was the Atopica's side effect) but othervise she seemed fine on it for the 4 years she had the medicine for.
I believe Sandimmun, human version of Atopica has been used for humans for years so the general side effects are pretty well known (not to say they are exactly same in dogs)